Search on: CASPASES, EFFECTOR 
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Descriptor English:   Caspases, Effector 
Descriptor Spanish:   Caspasas Efectoras 
Descriptor Portuguese:   Caspases Efetoras 
Tree Number:   D08.811.277.656.262.500.126.350
D08.811.277.656.300.200.126.350
D12.644.360.075.405.350
D12.776.476.075.405.350
Definition English:   A subclass of caspases that contain short pro-domain regions. They are activated by the proteolytic action of INITIATOR CASPASES. Once activated they cleave a variety of substrates that cause APOPTOSIS. 
Entry Combination - descr/qualif English:   Caspases, Effector/antagonists & inhibitors use Caspase Inhibitors
 
History Note English:   2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52220 
Unique Identifier:   D053470 

Occurrence in VHL:
 

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